Counting mpox cases in our nation’s big cities

December 2022

Colorized transmission electron micrograph of monkeypox virus particles (green) cultivated and purified from cell culture. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

Note: We stopped updating these case counts on December 15, 2022. While the disease continues to spread, new cases have dropped significantly, and the public health emergency is due to end in 2023.

As with many other infectious diseases, big cities have experienced higher case counts and more rapid spread of the mpox virus than elsewhere in the U.S. Because of this, big cities need a share of the vaccines that is proportionate to their much higher need.

More information about mpox – including national and state-level data, signs and symptoms, prevention, treatment, and more – can be found on the CDC website.

Case counts by city*

Last updated December 15, 2022. Click city name to see original source.

Austin (Travis Co.) 254
Baltimore 240
Charlotte (Mecklenburg Co.) 241
Chicago 1,109
Cleveland 92
Columbus 85
Dallas (Dallas Co.) 850
Denver 168
Detroit 141
Fort Worth (Tarrant Co.) 207
Houston 714
Kansas City 42
Las Vegas (Clark Co.) 288
Long Beach 125
Los Angeles (LA Co.) 2,249
Louisville (Jefferson Co.) 52
Memphis (Shelby Co.) 108
Milwaukee 35
Minneapolis 161
New York City 3,803
Oakland (Alameda Co.) 238
Philadelphia 549
Phoenix (Maricopa Co.) 473
Portland (Multnomah Co.) 175
San Antonio 189
San Diego (SD Co.) 457
San Francisco 841
San Jose (Santa Clara Co.) 209
Seattle (King Co.) 491
Tucson (Pima Co.) 60
Washington, D.C. 525
TOTAL 15,171

* Numbers shown are cumulative and include confirmed and probable cases for all BCHC member cities that have publicly available counts. When a BCHC member counts mpox cases by county, the county name is listed in parentheses. All other case counts are for the city itself.